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Practice Question

A nurse is preparing to administer cefazolin 250 mg 1M to a client. Available is cefazolin powder for injection 500 mg vial. The nurse reconstitutes the powder with 2 mL of sterile water for a concentration of 225 mg/mL. How many mL should the nurse administer? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Answer Choices:

Correct Answer:

1.1

Rationale:

Step 1: Identify the ordered dose and the reconstituted concentration

Ordered dose = 250 mg

Available concentration after reconstitution = 225 mg/mL

Step 2: Use the formula to calculate volume to administer

Formula:

Volume (mL) = Dose (mg) ÷ Concentration (mg/mL)

Calculation:

Volume = 250 ÷ 225 = 1.111… mL

Step 3: Round the final answer to the nearest tenth

Rounded Volume:

1.1 mL

Final Answer:

1.1 mL

Educational Insight

Reconstituting powdered medications like cefazolin requires careful attention to the resulting concentration, as it directly impacts dosing accuracy. This question highlights the importance of dividing the prescribed dose by the concentration obtained after reconstitution. Since IM injections require precision and typically involve small volumes, rounding to the nearest tenth ensures both accuracy and safe administration. Proper technique in reconstitution and dose calculation helps ensure effective treatment and minimizes complications.

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This question is from Dosage Calculation - PN Fundamentals which contains 5 questions.

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Dosage Calculation - PN Fundamentals

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Question Details
  • Category: LPN - Nursing Exam(s)
  • Subcategory: ATI Exams
  • Domain: DOSAGE CALCULATION PN
  • Answer Choices: 1
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