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RN Nursing · Renal and Urinary Disorders

Dialysis: Hemodialysis and Peritoneal Dialysis Nursing Review

By Nurse Jude · Updated June 19, 2026

A focused nursing study guide comparing hemodialysis and peritoneal dialysis, including access care, complications, dietary restrictions, and key NCLEX points.

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Dialysis replaces kidney function in patients with end-stage renal disease. This note compares hemodialysis and peritoneal dialysis, focusing on access, complications, dietary needs, and high-yield nursing priorities for the NCLEX.

Hemodialysis vs Peritoneal Dialysis

  • Access: Hemodialysis uses an AV fistula, AV graft, or central catheter; peritoneal dialysis uses a Tenckhoff catheter.
  • Location: Hemodialysis is performed at a dialysis center or home; peritoneal dialysis is done at home.
  • Frequency: Hemodialysis 3 times weekly; peritoneal dialysis daily (4-6 exchanges).
  • Duration: Hemodialysis 3-5 hours per session; peritoneal dialysis 30-60 minutes per exchange.
  • Anticoagulation: Required (heparin) for hemodialysis; not required for peritoneal dialysis.
  • Main infection risk: Bloodstream infection in hemodialysis; peritonitis in peritoneal dialysis.

Hemodialysis Access

  • AV fistula joins an artery and vein — the gold standard with the lowest complication rate.
  • AV fistula requires 4-8 weeks to mature before use.
  • Assess thrill (vibration) and bruit (whooshing sound) daily to confirm patency.
  • Never take blood pressure, draw blood, or apply tight clothing on the fistula arm.
  • AV graft uses synthetic tubing and matures faster but has higher complication rates.
  • Central venous catheter is temporary and carries the highest infection risk.

Hemodialysis Complications

  • Hypotension — most common complication, from rapid fluid removal. Manage by slowing fluid removal and placing the patient in Trendelenburg.
  • Muscle cramps — from fluid shifts; treat with slower fluid removal and saline.
  • Disequilibrium syndrome — confusion and seizures from rapid urea removal; prevent with slower initial dialysis. Most common after the first sessions.
  • Access site infection — redness, warmth, or drainage; requires strict aseptic technique.
  • Bleeding from anticoagulation — apply direct pressure to the access site.

Hemodialysis Nursing Care

  • Obtain pre-dialysis weight to determine fluid removal goal; post-dialysis weight confirms fluid removed.
  • Monitor vital signs before, during, and after treatment.
  • Assess access site for thrill and bruit before each session.
  • Monitor for hypotension, cramping, and bleeding during treatment.

Peritoneal Dialysis

  • Uses the peritoneum as a natural filter.
  • Dialysate is infused through a Tenckhoff catheter into the peritoneal cavity.
  • Wastes move from blood into dialysate during the prescribed dwell time.
  • Dialysate is drained and discarded; exchanges occur 4-6 times daily.
  • Warm dialysate to body temperature before infusion to prevent cramping.

Peritoneal Dialysis Complications

  • Peritonitis — most serious complication; presents with cloudy effluent, abdominal pain, and fever.
  • Obtain a culture of the effluent before starting antibiotics; antibiotics are added to the dialysate.
  • Exit site infection — redness, tenderness, or drainage at the catheter site.
  • Catheter malfunction — from kinking, fibrin clots, or constipation; enemas may be needed.
  • Respiratory distress — dialysate pushes on the diaphragm; elevate the head of the bed.

Peritoneal Dialysis Nursing Care

  • Use strict aseptic technique for all connections to prevent peritonitis.
  • Monitor effluent for cloudiness and measure output to calculate net fluid removal.
  • Keep catheter exit site clean and dry; report redness or drainage promptly.

Dietary Restrictions

  • Hemodialysis: strict fluid restriction (1-2 L daily) and strict potassium restriction (avoid bananas, oranges).
  • Peritoneal dialysis: less strict fluid and potassium limits due to continuous treatment.
  • Both: phosphorus restriction (avoid dairy, nuts) and increased protein to replace losses.

Nursing Assessment

  • Weigh patient daily before and after dialysis to assess fluid removal.
  • Monitor vital signs, especially blood pressure.
  • Assess access site for thrill, bruit, redness, or drainage.
  • Monitor labs: BUN, creatinine, potassium, phosphorus.
  • Assess for fluid overload: edema, crackles, JVD, dyspnea.

Patient Teaching

  • Hemodialysis: protect the fistula arm; check thrill daily; avoid tight clothing and blood pressure on that arm.
  • Peritoneal dialysis: use sterile technique; report cloudy effluent immediately.
  • Weigh yourself daily and follow fluid and dietary restrictions.
  • Take medications as prescribed; some are held before dialysis.
  • Report signs of infection: fever, redness, swelling, drainage.

Common NCLEX Traps

  • Absence of thrill or bruit indicates AV fistula clotting — report immediately.
  • Never take blood pressure or draw blood from the fistula arm.
  • Peritonitis presents with cloudy effluent, not just abdominal pain.
  • Disequilibrium syndrome occurs after the first hemodialysis sessions.
  • Warm dialysate to body temperature; cold causes cramping.
  • Peritoneal dialysis requires sterile technique; hemodialysis access care is aseptic but not sterile to the same degree.

Key takeaways

  • AV fistula is the gold standard for hemodialysis — check thrill and bruit daily, and never use that arm for BP or blood draws.
  • Peritonitis is the most serious peritoneal dialysis complication — suspect it with cloudy effluent, fever, and abdominal pain.
  • Hypotension and disequilibrium syndrome are the highest-yield hemodialysis complications.
  • Both modalities require low phosphorus and high protein; hemodialysis adds strict fluid and potassium restrictions.
  • Always obtain pre- and post-dialysis weights to evaluate fluid removal.

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